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Pregnant or nursing mothers, or those taking any medication, should consult a healthcare professional prior to use

Abbreviations AUD alcohol use disorder AUDIT Alcohol Use Disorders Identification Test DPP-IV dipeptidyl peptidase-IV Ex4 Exendin-4 GLP-1 glucagon-like peptide-1 GLP-1R GLP-1 receptor LDTg laterodorsal tegmental area NAc nucleus accumbens NTS nucleus tractus solitarius SNP single nucleotide polymorphism VTA ventral tegmental area Funding The mini-review is supported by grants from the Swedish Research Council (2023-2600)

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While the published study focused primarily on SGLT2is and reported improvements in DHEAS and menstrual irregularity, our meta-analysis included a broader range of interventions (GLP-1 RAs alone and in combination) and found more pronounced hormonal benefits, such as significant reductions in FAI and testosterone with SGLT2is, outperforming GLP-1 RAs in these aspects

Vitamin K1, known as phylloquinone, is dietary vitamin K that can be sourced from green, leafy vegetables