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So, even though these two defenses against oxidative stress do not exhibit any significant downregulatory malfunction, a lack of their upregulation during a period of increased oxidative stress can contribute to the enhanced ROS experienced by the MUN placenta by not effectively removing enough superoxide and hydrogen peroxide from the placental environment

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Nonetheless, several studies and meta-analyses have failed to demonstrate a substantially high risk of pancreatitis

When they do not function properly, overall cellular health declines

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