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Drugs from the GLP-1RA group targeting the GLP-1R, reduce damage caused by hypoperfusion through the interaction of pleiotropic pathways and signaling cascades, including those involved in mutual regulation of the gut and brain, thereby opening up new prospects for the treatment of neurocognitive disorders

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When its disrupted, you get an immune system thats either underperforming, overreacting, or doing both simultaneously in different tissues

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