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It is difficult to give a structural explanation of the ligand-specific effect of the L32A mutation by comparing the two ligand-bound forms of the ECD, because the structural differences in this region are quite subtle
Its significance is rooted in its endogenous nature
McGregor, University of Wisconsin-Madison, United States Updates Copyright 2023 Yan, Xu, Zhou, Zhang, Zhang, Meng and Lv
Thyroid Autoantibodies and Thyroid Function in Subjects Exposed to Chernobyl Fallout during Childhood: Evidence for a Transient Radiation-Induced Elevation of Serum Thyroid Antibodies without an Increase in Thyroid Autoimmune Disease
Neither is a failure of the molecule
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