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Together, these findings suggest that cellular resistance to cuproptosis also depends on a hierarchically organized copper-buffering system, in which mtGSH provides rapid, dynamic metal buffering, whereas metallothioneins confer sustained high-affinity sequestration to prevent mitochondrial copper overload

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Zhang Y, Guo Q, Fang X, et al

pylori PNP, and a good lead compound to design more potent inhibitors, but its effect should still be tested in vivo

[1] Large Fractures Fractures occur when direct trauma is inflicted on the bone or when extreme force is transmitted at an angle through the bone