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Additionally, the existing literature on GLP-1 and reward processing has focused almost exclusively on food rewards

Growth hormone stimulation can promote insulin resistance, directly conflicting with retatrutide's metabolic goals and creating unpredictable glycaemic risks

Women of childbearing age should use contraception while on tirzepatide and discontinue the medication at least 2 months before attempting conception to allow complete washout given the long half-life

Vitamin B12 plays a key role in energy production, metabolism, and neurological function

A growing body of evidence supports the pivotal role of placental oxidative stress, mitochondrial dysfunction, and ferroptosis in promoting the development of GDM