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[1] That pharmacology creates a predictable psychological trap: you stop injections, nothing dramatic happens immediately, you assume you are safe, and then appetite and food noise surge later, right when motivation is lowest

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5.16 Exacerbation of Other Conditions Estrogen therapy, including the Estradiol Transdermal System, may cause an exacerbation of asthma, diabetes mellitus, epilepsy, migraine, porphyria, systemic lupus erythematosus, and hepatic hemangiomas

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