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Een belangrijke nuance is dat carnitine door darmbacterin kan worden omgezet in trimethylamine (TMA), dat op zijn beurt in de lever kan worden verwerkt tot trimethylamine N-oxide (TMAO)

Before considering combination approaches, patients should understand that adding a second medication increases complexity, monitoring burden, side effect risk, and cost

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10.1039/P29960002497 10.1039/P29960002497 [DOI] [Google Scholar] Kachadourian R, Johnson CA, Min E et al (2004) Flavin-dependent antioxidant properties of a new series of meso-N, N-dialkyl-imidazolium substituted manganese(III) porphyrins