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Biomedicine 11(4):999 Chitturi J, Santhakumar V, Kannurpatti SS (2021) Traumatic brain injury metabolome and mitochondrial impact after early stage Ru360 treatment

Peptide chains clump together into insoluble complexes that cannot be reversed by re-cooling

doi: 10.1186/1741-7015-9-48 27

McConnell N, Campbell S, Gillanders I, Rolton H, Danesh B

In vivo animal experiments showed that daily administration of NNMTi for 28 days to dietinduced obese (DIO) mice significantly upregulated the expression of lipolysisrelated genes (such as ATGL and HSL) and downregulated lipogenesisrelated genes (such as FAS and ACC), indicating that NNMTi effectively promotes fat breakdown and inhibits fat synthesis