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Oral NAC at 600-1800 mg daily is well-absorbed and documented to raise intracellular glutathione levels over weeks of use

Dose-dependent nausea was the most common complaint

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While IGF-1 has important physiological functions, elevated levels carry potential concerns including increased cell proliferation that may support tumor growth in individuals with cancer or pre-cancerous conditions, accelerated aging processes through growth pathway activation, potential cardiovascular effects with chronic elevation, and metabolic consequences including effects on glucose and lipid metabolism