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SCFAs are synthesized from indigestible carbohydrates by bacteria such as Firmicutes , Bacteroidetes , and Bifidobacteria [145], as well as Akkermansia, Lactobacillus [142, 146], and Prevotella [147]

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Research on depressed patients found that low NPY levels correlate with suicidal ideation, suggesting that NPY deficiency may identify particularly vulnerable individuals