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Experimental models demonstrate that restoring glutathione normalizes mitochondrial redox status and improves endothelial and cardiovascular function, supporting a causal role for mitochondrial glutathione depletion in cardiovascular aging (17-18)

Additionally, foods high in vitamin C, such as citrus fruits (oranges, lemons, grapefruit) and strawberries, can help regenerate glutathione in the body

Gpxs exist in multiple isoforms, with different cellular localization and different substrate specificity (15)

doi: 10.1038/sj.npp.1300413 61 LongoFKlannE

The process is generally well-tolerated, with minimal side effects for most individuals