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A 2017 review published in the International Journal of Molecular Sciences has found that nattokinase may be a beneficial antithrombotic agent to reduce the risk of cardiovascular disease ( 47 )

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The global clinical trials market size is estimated at USD 87.42 billion in 2025 and is predicted to increase from USD 91.66 billion in 2026 to approximately USD 158.92 billion by 2035, expanding at a CAGR of 615% from 2026 to 2035

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