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Additionally, GF mice exhibit a decreased count of CD4+ T cells in their spleens, along with a reduction in both the number and size of germinal centers within the spleen, implying that the GM plays a crucial role in modulating systemic immunity (121) ( Table 2 )

This includes a complete metabolic panel, fasting insulin, HbA1c, fasting glucose, lipid panel (complete with LDL particle count if available), IGF-1, growth hormone levels (random and stimulated if possible), liver enzymes (ALT, AST, GGT), kidney function markers (creatinine, BUN, eGFR), complete blood count, and thyroid panel

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