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Increased levels of GH and IGF1 in the circulation stimulate the release of somatostatin, which interacts with somatostatin receptors and negatively regulates GH secretion from the anterior pituitary
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But here is where it gets complicated
DISCUSSION In this NMA, GLP-1RA had a significantly better effect in reducing liver fat content and improving cardiometabolic risk parameters, including BMI and WC, in overweight or obese patients with NAFLD or NASH
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