This study was able to corroborate the previously reported elevations of miR-122, but failed to replicate the earlier report for miR-192 (Starkey Lewis et al
doi: 10.5173/ceju.2020.1975 135 WuXLuMYunDGaoSChenSHuLet al
Available online at: February 18, 2022)
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The effects of NTZ were compared to those of the standard antioxidant, N-acetyl cysteine (NAC), as a well-documented hepatoprotective agent known to inhibit ER stress, and to those of 4-phenyl butyrate (4-PBA), a standard ER stress inhibitor ( 2 Materials and methods 2.1 The experimental animals Currently, we included 36 adult male albino Wistar rats (with a body mass range equal to 190230 g, 810 weeks of age) supplied by the Faculty of Veterinary Medicine, Zagazig University. Rats were kept in hygienic laboratory conditions, including temperature (22C 3C), relative humidity (60% 10%), and normal light/dark cycle