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Tranilast: a review of its therapeutic applications

Because it is a small molecule, it is studied orally/sublingually in the literature

Dihexa is taken by mouth as one or more capsules once daily, swallowed whole with or without food

Compellingly, GCN2 expression in CD4 + T cells is associated with anergy and tolerance to tissue (tumor) damage [151, 152], probably being an interesting molecular target for antagonism, improving antitumor immunity while also restraining tumor cells survival, at least for some tumors

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