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Size and shape of ligands: As long as ligands are not excessively rigid and bulky their size is less important than the size of the metal in determining the number of ligands that coordinate

As predicted, the specific GST inhibitors displayed parasite growth inhibition at EC 50 of 6.9 and 4.4 M for S-hexylglutathione and ellagic acid, respectively (Supplementary Figure S2C)