Additionally, it downregulates SLC7A11 channel protein expression while upregulating ALOX3, further promoting ferroptosis ( Multiple studies have also revealed that Saikosaponin A can induce ferroptosis in hepatocellular carcinoma (HCC) cells, both in laboratory settings and in living organisms
Oller J, Gaband-Rodrguez E, Ruiz-Rodrguez MJ, Desdn-Mic G, Aranda JF, Rodrigues-Diez R
doi: 10.1186/s12974-024-03116-5 17 HegdekarN.SarkarC.BustosS.RitzelR
[197] explored another approach for utilizing ketosis in PD, investigating how a ketone ester drink might affect exercise endurance in individuals diagnosed with PD
It is important to note that all scientifically verified effects described below are based on preclinical research, including in vivo rodent models and in vitro cellular systems