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In this issue of Diabetologia , Maida et al

LiKO-KD, n = 8 mice

One of the major problems in blood-sugar is the free radical damage and oxidative stress

Although these techniques offer high sensitivity and excellent molecular specificity, their clinical translation is limited by poor tissue penetration, dependence on exogenous tracers, and predominant use in preclinical or intraoperative experimental settings rather than routine diagnostic imaging

Patients with end-stage renal disease undergoing dialysis can develop a secondary carnitine deficiency due to the unrestricted loss of L-carnitine through the dialyser, and L-carnitine has been used for treatment of some patients during long-term haemodialysis