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The Many Faces of Vitamin B12: Catalysis by Cobalamin-Dependent Enzymes

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Many people with a deficiency describe deep fatigue, including an "afternoon crash." With infrequent dosing, blood levels can peak and then taper before the next visit

In addition, facilities for detecting the radioactive B12 in a 24-hour collection of urine slowly vanished as did sources for intrinsic factor that could be used in humans

While some treatments, like HCG injections, are most effective when paired with a low-calorie diet, others like Lipotropic and B12 injections do not require strict dietary changes