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In human studies, oral ingestion of collagen peptide preparations has been shown to induce transient postprandial increases in specific peptides such as ProHyp and GlyProHyp in plasma, supporting their systemic availability and potential to reach dermal targets [46]

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Specifically, the combination of BPC-157s gastrointestinal cytoprotection, GHK-Cus extracellular matrix remodeling, TB-500s cellular migration, and KPVs anti-inflammatory resolution addresses all four phases of gut mucosal healing in a single preparation

The induction of genes encoding a sodium inducible calcium binding protein, a protein phosphatase, a PAL and GSTF7 were observed (Naidoo et al., 2007)