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Endocrinology 141 , 181189 (2000)

Postprandial gut hormones are regulated by DPP4 expressed by gut epithelial, endothelial, and immune cells (9), and systemic DPP4 has been implicated in FXa/PAR2-mediated adipose tissue inflammation (40)

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This is the formidable challenge that traditional treatments struggle to overcome, and it's precisely where the potential of a systemic agent like BPC 157 becomes so compelling

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