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Data availability The datasets utilized and/or analyzed in this study are available from the corresponding author upon reasonable request

Discard any remaining medication after the recommended timeframe, even if the vial is not empty

Mounjaro may affect how oral birth control pills are absorbed, particularly when starting treatment or increasing the dose

Ongoing research is examining several important questions regarding tirzepatide's long-term safety profile: Thyroid cancer surveillance : Prospective monitoring of thyroid-related adverse events in large patient cohorts Pancreatic safety : Evaluation of pancreatitis and pancreatic cancer risk with extended exposure Gallbladder disease : Assessment of cholecystitis and cholelithiasis incidence with rapid weight loss Comparative safety : Head-to-head comparisons with other incretin-based therapies The American Diabetes Association and American Association of Clinical Endocrinology (AACE) continue to recommend tirzepatide as an effective treatment option for type 2 diabetes and obesity, with the understanding that ongoing surveillance will further clarify its long-term safety profile

in the past two decades, with a 49 percent increase from 2016 to 2021 alone