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The 3D structures of the homologous Mn and Fe superoxide dismutases have the same arrangement of alpha-helices, and their active sites contain the same type and arrangement of amino acid side-chains

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

Statistics and reproducibility Data from in vitro epithelial cytotoxicity, fungal proliferation, 13-HODE release, individual metabolites and fungal respiration assays were analyzed using GraphPad Prism version 10 (GraphPad Software, La Jolla California USA)