Clostridium butyricum produces the postbiotic butyrate which stimulates GLP-1. Bifidobacterium infantis produces the postbiotics acetate and lactate which feed bacteria such as Akkermansia and Butyricum, promoting an ecosystem in the gut that supports a healthy gut lining and naturally boosts GLP-1
Both drug classes were equally effective in reducing combined major adverse cardiac events such as heart attack, stroke, and death from cardiovascular disease, compared to people with diabetes who were not taking the drugs.[3] The rate of hospitalization for heart failure was 32% less in patients taking SGLT2 inhibitors compared to patients not taking the drugs, especially in those with more severe cardiovascular disease risk
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There is also the likelihood that a probiotic bacterias action may depend on the individuals CKD stage (Tian et al., 2022)
