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Given that hepsin / mice were reported to have elevated mRNA levels of mitochondrial Cpt1b , Cpt2 , and Cox7a1 in adipose tissues compared with wild-type mice, suggesting a regulatory role for hepsin in metabolism (Li et al

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GLP-1 research compounds are peptides designed to interact with receptors involved in appetite regulation, insulin signaling, gastric emptying, energy metabolism, and glucose homeostasis

However, our results do not explain whether metformin directly affects the ANS or if the improvement of metabolic dysfunction indirectly normalizes the ANS activity