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The effect of loss of LC neurons in the early stage of AD have been reported by transgenic AD mouse model, in which LC destruction in the pre-plaque stage caused aggravation of cognitive damage [126]

Notably, half of Pacific males aged 65 years or over were estimated to have gout

doi: 10.3389/fendo.2024.1358404 Received 19 December 2023 Accepted 15 February 2024 Published 05 March 2024 Volume 15 - 2024 Edited by Chen Liu, University of Texas Southwestern Medical Center, United States Reviewed by Surbhi Gahlot, University of Texas Southwestern Medical Center, United States Carlos Manuel Zapata-Martn del Campo, National Institute of Cardiology Ignacio Chavez, Mexico Updates Copyright 2024 Raij and Raij

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