Subgroups analysis Given that the primary hypothesis of this study was null, subgroup analyses were conducted considering drugs received, polymorphism types, and treatment outcomes
Data availability The primary individual-level datasets used in this study originated from the Integrated Data Infrastructure managed by Stats NZ
Edibles are smoke-free, making them a gentler option for the lungs and overall respiratory system
Secondary outcomes will compare percent days smoke-free, changes in nicotine dependence, and motivation, confidence, and intentions to quit smoking by the regulatory scenarios
Given that the ASL is involved in innate defense and that we observed dysregulation of innate defense proteins, our data suggest that pulmonary defenses may be altered by tobacco exposure