Forms of Vitamin B12 and Who They Suit B12 Form How Its Taken Best For Tablets/Capsules Swallowed with water Mild deficiency, general wellness, everyday convenience Sublingual tablets Dissolve under the tongue People who may not absorb well through the gut Nasal spray Sprayed into the nostril Those who dislike pills or injections Injections Given in clinic or at home (prescribed) Confirmed deficiency, absorption issues, and faster results Oral tablets and capsules are convenient, but they must pass through the digestive system, which can limit absorption in people with gut issues, low stomach acid, or certain surgeries
Give the injection slowly and evenly
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Supplement Absorption Mechanisms Oral B12 supplements rely on two absorption pathways
They found, with low certainty, that women who took vitamin B 12 supplements (50 or 250 ug/day in conjunction with supplemental iron and folic acid) during pregnancy had a clinically meaningful increase in vitamin B 12 status (mean increase of 60.89 pmol/L (95% CI 40.86 to 80.92) as did their infants at 6 weeks or 3 months of age (mean increase 71.89 pmol/L (95% CI 20.23 to 123.54)