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4 They are consistently associated with: Significant weight reduction Decreased central adiposity Potential improvements in cardiovascular markers Some emerging evidence even suggests they may help with vasomotor symptoms 5 (like hot flashes), though this area requires further study

Cochrane Database Syst Rev 1:Cd011451

In the DURATION-1 and -5 trials, exenatide once weekly was shown to reduce HbA1c more significantly than twice daily administration (1.9% vs