Thiostrepton 6138234 with ~440 nm often used

with ~440 nm often used as the peak

Its chemical formula is C₅₁H₉₈O₆ and its molecular weight is ~807

histone acetylation

but is not compatible with a blue light illuminator or laser-based scanner

prodrug-free) to distinguish effects due to conversion

Thiostrepton 6138234 with ~440 nm often usedThiostrepton is a cyclic peptide antibiotic isolated from Streptomyces azureus. It targets a wide variety of gram negative and gram positive bacteria, especially those causing skin infections. It has been used as a marker for selection of recombinant Streptomyces cultures. Additionally, thiostrepton has been shown to inhibit FOXM1, a gene commonly overexpressed in cancer cell lines, thus inhibiting cancer cell growth. Thiostrepton functions by binding