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It has been hypothesized that ALS develops as an interaction between genetic and environmental factors

4ah) submitted to the NCBI Sequence Read Archive database were GSE248829 and PRJNA1456226, respectively

Isoliquiritigenin inhibits NLRP3 inflammasome activation with CAPS mutations by suppressing caspase-1 activation and mutated NLRP3 aggregation

We generated GGT1 knockdown cell lines using CRISPRi approaches and GGT1 KO cell lines (polyclonal and single-cell clones) using CRISPRCas9 approaches