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In healthy humans, the plasma betaine concentration ranges from 20 to 70 mol/L (Lever et al., 1994

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It therefore follows that BPC 157 is a novel cytoprotection mediator, one that is very safe and showed no side effects in clinical trials (i.e., in use for ulcerative colitis), and wherein a lethal dose (LD1) was not achieved in toxicology studies (for review, see [1,9,33,93])

Key points Key messages from the paper Incretin analogues (semaglutide, tirzepatide) provide effective glucose control in type 2 diabetes mellitus (T2DM) and major weight losses in people without diabetes