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The encapsulation of DDA-GSH-AuNCs into PLGA nanoparticles does not alter the well documented biocompatibility of PLGA as evident from similar cellular viability of MCF-7 cells upon exposure to empty PLGA nanoparticles or PLGA nanoparticles encapsulating DDA-GSH-AuNCs in a wide range of nanoparticle concentration (4500 g/mL) as shown in Fig

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Aoi et al., (47) investigated the effect of glutathione intake on exercise-induced muscle metabolism and fatigue in mice and humans

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A microdosing chart gives them a shallow entry point

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