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Obesity and overweight are serious conditions that can be associated with some of the leading causes of death such as heart disease, stroke and diabetes, said John Sharretts, MD, director of the Division of Diabetes, Lipid Disorders and Obesity in the FDAs Center for Drug Evaluation and Research in an FDA press release announcing Zepbounds approval

This could lead to a more consolidated market with fewer, but stronger, players

Mentally preparing with the knowledge that initial side effects are normal and temporary

They are also associated with a number of syndromes (Table 1)

For patients with symptoms, A1c greater or equal than 10% or blood glucose greater or equal than 300 mg/dL, combined injectable therapy should be considered, including basal insulin plus bolus insulin or GLP-1 RA or premixed insulin