A reasonable baseline is around 0.8 grams per kilogram of body weight per day (g/kg/day), or approximately 0.36 grams per pound (g/lb)
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This helps to distract the brain from the immediate injection pain, flattens the area so it doesnt leave the Botox as a small lump, and helps to slightly spread the area of coverage for the Botox to work
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This may happen because too much insulin interferes with fibrinolysis, and too much glucose triggers coagulation