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If you dont have access to a dermatology expert, these are the simple rules that you need to follow when mixing tranexamic acid and retinoids: Make sure your skin is completely free from irritation before introducing a new product Start off by using the new ingredient once or twice a week and build up the frequency as your skin adjusts Stop using all active ingredients at any sign of irritation until the symptoms have cleared up Avoid overwhelming your skin by using too many strong actives at the same time of day If irritation continues, speak with a professional Want personalised advice