Brunner went on to describe compoundings growing prevalence and controversy in light of the emergence of GLP-1 drugs, originally indicated for weight loss and diabetes and sold under brands such as Ozempic, Wegovy and Mounjaro
10.1111/j.1463-1326.2012.01557.x [DOI] [PubMed] [Google Scholar] 190.Lorenz M, Pfeiffer C, Steinstrsser A, Becker RH, Rtten H, Ruus P, et al
Dietary considerations may play a supportive role, although these are not proven to prevent gallstones in GLP-1 users: Maintain regular meal patterns rather than severely restricting calories, which helps stimulate regular gallbladder contraction Include moderate amounts of healthy fats in the diet (such as olive oil, nuts, and oily fish) to promote gallbladder emptying Ensure adequate hydration to support bile flow Avoid very low-calorie diets unless under specialist supervision For individuals at particularly high risksuch as those with a history of gallstones, rapid weight loss, or multiple risk factorssome specialists may consider ursodeoxycholic acid (UDCA) prophylaxis
B Treatment Goals 10.3 For patients with diabetes and hypertension, blood pressure targets should be individualized through a shared decision-making process that addresses CV risk, potential adverse effects of antihypertensive medications, and patient preferences
& Balboula, A