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The other thing that I would like to ask you about is, in the sauna, of course, there's vasodilation, and perfusion of blood to the brain is a wonderful way to enhance cognition

Patients with hypermobility EDS have an increased risk of developing inflammatory diseases, including celiac disease 54 and eosinophilic esophagitis, 53 compared to the general population and also have an increased prevalence of autoantibodies, including antinuclear and antiphospholipid antibodies

One study demonstrated that upregulation of Nrf2-regulated genes was inhibited in insulin-treated cerebral endothelial cells after 6 h of high glucose exposure, suggesting that insulin treatment can prevent or reduce oxidative stress (Arcambal et al., 2019)

By contrast, in this latest work, we leveraged an LLM (OpenAIs GPT-4 model) for zero-shot classification through prompt engineering, an iterative process where users provide conversational instructions and examples to the LLM to optimize performance (28, 34)

Paraffin sections were stained using the AB-PAS method and then examined and quantified for goblet cells under a microscope ( TABLE 2 Scoring criteria for histological changes