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A granuloma may grow to be quite large, forming a smooth spherical mass as in the figure above, and can be either broad-based or narrow-necked

Furthermore, L cells remained functional as primary colonic organoids derived from IL-10 -/- mice showed a secretory response towards stimulation with the bile acid deoxycholic acid (DCA) that did not significantly differ from that of Wt organoids (3.3 0.36 vs 2.1 0.28 fold increase), despite overall reduced secretion of GLP-1 per living cell ( Figure 2I )

Table 3 represents the concomitant medications at the baseline

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