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Front Endocrinol (Lausanne)10(JAN):433707

The value equation depends entirely on individual response and circumstances

As these assets progress through the pipeline, innovators will need to navigate an increasingly crowded field and seek differentiation on multiple dimensions, including efficacy, tolerability, convenience, durability and quality of weight loss that distinguishes between fat vs

However, emerging data and mechanistic plausibility suggest that certain populations may be at higher risk of suboptimal intake or depletion, particularly with prolonged therapy, rapid weight loss, restricted dietary variety or pre-existing marginal nutrient status