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The label also states that Mounjaro is not recommended in patients with severe gastroparesis, and it includes warnings for acute kidney injury due to volume depletion in patients with reactions that may cause dehydration

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Taking a single, low dose (200 mg) of ibuprofen with food and plenty of water, at a time when semaglutide side effects are least pronounced (typically several hours after injection or in the afternoon if using oral formulations), may reduce gastric irritation