Definition Box Glycosaminoglycans (GAGs): Long, unbranched polysaccharides (including hyaluronic acid, chondroitin sulfate, and dermatan sulfate) that hydrate the extracellular matrix and support tissue elasticity and structural cohesion
The peptide stimulates collagen synthesis, improves skin elasticity, and reduces fine lines through gene expression changes favoring youthful tissue
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Common examples include semaglutide (Ozempic, Wegovy, Rybelsus), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), and tirzepatide (Mounjaro), which is a dual GLP-1 and GIP receptor agonist
Although these observations are interesting, the comparison with historical control individuals is a serious limitation in the interpretation of these results