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In addition, combining GLP-1RAs with other therapeutic agents, such as sodium-glucose cotransporter 2 inhibitors (SGLT2i), has shown synergistic effects in reducing liver stiffness and improving overall liver health ( 6.3 HCC Preliminary evidence suggests that GLP-1RAs may provide protective effects against HCC development

Miga-mediated endoplasmic reticulum-mitochondria contact sites regulate neuronal homeostasis

The variant, rs10305420, is a missense variant within the gene itself, meaning that it changes the protein encoded by the gene