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GLP-1 receptors exist in the dorsal vagal complex of the brainstem

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PlexusDx offers a Precision Peptide Genetic Test that identifies common variants in these peptide-metabolism genes, potentially adding context to a provider conversation about whether standard GLP-1 dosing, microdose protocols, or combination therapies may align better with an individual's genetic profile

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Gameiro A, Reimann F, Habib AM, OMalley D, Williams L, Simpson AK, Gribble FM (2005) The neurotransmitters glycine and GABA stimulate glucagon-like peptide-1 release from the GLUTag cell line