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Jastreboff AM, Kaplan LM, Frias JP, Wu Q, Du Y, Gurbuz S, Coskun T, Haupt A, Milicevic Z, Hartman ML

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Preclinical in vivo evaluation of rapamycin in human malignant peripheral nerve sheath explant xenograft

Under stress conditions, activated microglia release inflammatory factors that drive neuroinflammation, whereas in a tissue repair state, they promote neuroprotection ( 42 significantly increased TNF- mRNA expression, this effect was suppressed by choline deficiency and Lico E treatment