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The reasons for the wide-spread use of this test are the ease of performing the single intervention, the reproducible and spontaneous pain-related responses that can be observed in unrestrained animals, and finally, the 2 separately interpretable readouts

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A retrospective study in Argentina (20052023) involving over 54,000 men found that exposure to prolonged heatwaves during spermatogenesis led to significant reductions in sperm concentration, motility, and normal morphology (127)

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