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Pharmacopeial Convention standards
By activating both GIP and GLP-1 receptors, tirzepatide enhances glucose-dependent insulin secretion from pancreatic beta cells, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying
Khavinson VK, Izmaylov DM, Obukhova LK, Malinin VV (2000) Effect of epitalon on the lifespan increase in Drosophila melanogaster
Retatrutide might be better suited for those who require massive weight loss and can control or tolerate the increased risk of stomach and heart side effects
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