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Recombinant adeno-associated serotype 9 viruses with Ap2 promoter for SIRT3 overexpression in adipocytes (AAV- Ap2 -SIRT3) or the empty vector (AAV- Ap2 ) were acquired from GeneChem Co, Ltd (Shanghai, China)

Daily fluctuations of one to four pounds are normal and do not reflect actual fat gain or loss

Insulin like growth factor-1 (IGF-1) acts as a downstream messenger that directly supports muscle cell growth and muscle protein synthesis

Aug 2010;160(2):264-271 e261

164 The carnitine palmitoyl transferases (CPT), the rate-limiting enzymes in the FAO pathway, transport long-chain acyl-CoA from the cytosol to mitochondria